Hybridises with :

• Cowslip (Primula veris) to produce False Oxlip (Primula elatior).
• Oxlip (Primula elatior) to produce (Primula × digenea).

Primin and Primetin are quinones found in the Primrose species, especially primula obconica, an ornamental Primula, and are known to cause contact allergic reactions. Primin was one of the first molecules to be recognised as causing allergic dermatitis in gardeners and florists. The substance, and many others, was being liberated by the trichomes, short sharp hollow hairs, on the plant. Primin is now used in a standard allergenic patch to test sensitivity of individuals to Primula species. Primetin is a known contact sensitiser in Mistassini Primrose (Primula mistassinica Michaux), a Bird's-eye type primrose which is not native to the UK but grows by Lake Mistassini.

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